Pio Amato, a 14 year-old member of a small Romani community in Calabria, is in a hurry to grow up. Pio follows his older brother Cosimo everywhere and from him he learns how to hustle and how to navigate the streets of his hometown. One night Pio sets out to prove to his brother that he is as good or better than him but, when things go wrong, a series of events will forever change the way he sees the world.
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Twelve-year-old Simone feels painfully disconnected from the world after witnessing the brutal death of her mother. Simone, a solitary multimedia artist in her twenties, is struggling to control her crushing panic attacks and keep her day job in an underground parking lot. And Simone, a sixty-year-old physicist, is giving a conference on the nature of time. The three Simones’ lives are intertwined in a labyrinthine meta-world where timeframes overlap, characters multiply, and storylines repeat and expand. But, for all its shuttling forward and back through time, ENDORPHINE remains grounded in the Simones’ inner lives — it’s an artistic examination of scientific phenomena that also poignantly explores how people deal with trauma.
Queen Victoria strikes up an unlikely friendship with a young Indian clerk named Abdul Karim.